Protection of extract from pigeonpea leaves on myocardial ischemia reperfusion injury in rats / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 3382-3385, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-853869
ABSTRACT
Objective:
To investigate the protective effects of pigeonpea leaves on myocardial ischemia reperfusion injury in rats.Methods:
A model of myocardial ischemia reperfusion was established by ligating the anterior descending coronary arteries. Rats were administrated with extract from pigeonpea leaves (125, 200, and 500 mg/kg) before ischemia, and the size of myocardial infarction, arrhythmia score, and morphological changes of cardiomyocytes were determined.Results:
Compared with the model group, pigeonpea leaves could reduce arrhythmia severity and incidence (P<0.05 or 0.01) and the size of myocardial infarction (P<0.05). Pigeonpea leaves could ameliorate the pathological lesion.Conclusion:
Pigeonpea leaves have the protective effects on myocardial ischemia reperfusion injury in rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2015
Type:
Article
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