Clinical observation on Xueshuantong Injection in treatment of acute cerebral infarction patients with Clopidogrel resistance / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 2122-2126, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-854081
ABSTRACT
Objective:
To observe the effect of Xueshuantong Injection on platelet aggregation in acute cerebral infarction patients with Clopidogrel resistance (CR).Methods:
This study selected acute cerebral infarction patients with CR from March 2012 to August 2014 in Tianjin Hospital. Patients (104 cases) were randomly divided into two groups (n = 52). The patients in the control group were treated with Western Medicine and Clopidogrel 75 mg/d, and the patients in treatment group were treated with Western Medicine and Clopidogrel 75 mg/d and given Xueshuantong Injection (5 mL dissolved in 0.9% saline 250 mL, iv drip). The two groups were treated for 14 d.Results:
The platelet aggregation in the two groups was reduced significantly after treatment (P < 0.05), and after treatment the platelet aggregation in the treatment group was lower than that in the control group (P < 0.05).Conclusion:
Xueshuantong Injection can reduce platelet aggregation in acute cerebral infarction patients with CR, and is a beneficial supplement therapy for CR.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2015
Type:
Article
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