Primary Malignant Melanoma of the Esophagus: A case report
Korean Journal of Pathology
;
: 694-696, 1998.
Article
in Korean
| WPRIM
| ID: wpr-85418
ABSTRACT
This report presents an unusual case of primary malignant melanoma in the midesophagus. The patient was a 36-year-old woman presenting with dysphagia and odynophagia. The resected esophagus and proximal stomach showed a dark purple large polypoid mass, measuring 6.0 3.3 2.0 cm, with a diffuse tan pigmentation of surrounding mucosa in the mid-esophagus and two small daughter nodules, up to 1.2 0.3 cm, in the lower esophagus near the gastro-esophageal junction. A microscopic examination revealed a malignant melanoma of epithelioid cell type confined to mucosa and submucosa with a diffuse melanosis. Cytoplasmic immunoreactivity for HMB 45 and S-100 protein were noted. An electron microscopic examination revealed large, loosely cohesive variable shaped cells with a few cytoplasmic premelanosomes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach
/
Triacetoneamine-N-Oxyl
/
Pigmentation
/
Nuclear Family
/
Deglutition Disorders
/
S100 Proteins
/
Epithelioid Cells
/
Cytoplasm
/
Esophagus
/
Melanoma
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Pathology
Year:
1998
Type:
Article
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