Study on pharmacological activity of new hybrids Amomum villosum (Spring No.1) / 中草药

ABSTRACT

Objective: To explore the pharmacological activities of volatile oil in new hybrids of Amomum villosum (Spring No.1) and compare to the female parent "Longfruit No.2". Methods: The auricle swelling model of mice was induced by xylene, the diarrhea model of mice was induced by 10% Senna, the writhing body model of mice was induced by 0.6% acetic acid solution to observe the pharmacological actions of volatile oil in "Spring No.1". Results: The volatile oil in both "Spring No.1" and "Longfruit No.2" had significant antidiarrheal effect, their effect was equivalent to the positive drug (Montmorillonite Powder). There was no significant difference in anti-inflammatory effect compared with the control group, the analgesic effect was significant. Both of them had the bidirectional regulation on gastric emptying. High dose of them had the stimulative effect in the small intestinal propulsion, and low dose of them had no significant effect. Conclusion: There is no significant difference in pharmacological activity between the new hybrid species "Spring No.1" and its female parent. It could be comparable to the traditional cultivars of A. villosum. This study provides a scientific basis for expanding A. villosum medicinal resources.