Chemical constituents from Euphorbia altotibetica / 中草药

ABSTRACT

Objective: To study the chemical constituents from the aerial parts of Euphorbia altotibetica. Methods: The compounds were isolated and purified by various chromatographic techniques and their structures were elucidated by spectral analysis. Results: Six compounds were isolated and their structures were identified as altotibetin E (1), proline (2), corchoionoside C (3), icariside B2 (4), 1-O-(9Z,12Z,15Z-octadecatrienoyl)-2-O-hexadecanoyl-3-O-α-(6-sulfoquinovopyranosyl) glycerol (5), and (2S)-2,3-O-dioctadeca-9Z, 12Z,15Z-trienoylglyceryl-6'-O-(α-D-galactopyranosyl)-β-D-galactopyranoside (6). Conclusion: Compound 1 is a new cembranoid diterpene named altotibetin E, compounds 2, 5, and 6 are isolated from the species of Euphorbia L. for the first time and the other compounds are firstly obtained from this plant.