Clinical observation on Yishen Juanbi Capsule combined with Western medicine for treatment of elder-onset rheumatoid arthritis / 中草药

ABSTRACT

Objective: To investigate the clinical effect of Western medicine combined with Yishen Juanbi Capsule on elder-onset rheumatoid arthritis (EORA). Methods: A total of 46 patients who had EORA were randomly divided into treatment group and control group. The treatment group including 3 males and 23 females was treated with Methotrexate, 10 mg once a week, and Etoricoxib, 60 mg once a day, by oral administration treatment. The control group including 2 males and 18 females was treated with Yishen Juanbi Capsule, four capsules per time, three times per day on the base of treatment group. The clinical effect and medicinal incidences of adverse effect in 4, 8, and 12 weeks were respectively investigated. Results: There was a significant difference between the treatment group and control group (P0.05). Conclusion: The clinical effect of Western medicine combined with Yishen Juanbi Capsule used in the treatment of the EORA is significant and safe.