Optimization of damp-proof excipients for Gushuling Granules / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 2005-2008, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-854453
ABSTRACT
Objective:
To evaluate the effect of the excipients on hygroscopicity of Gushuling Granules and optimize the damp-proof excipients.Methods:
Moisture absorption rate was used to optimize the type and ratio of materials; The concentration of ethanol, moisture absorption rate, formability, angle of repose, and appearance of Gushuling Granules were used to optimize the molding technology.Results:
The best damp-proofing excipients were as follows the hybrid materials were lactose-mannitol 41, medicine-auxiliary ratio of 12, and with 85% ethanol to granulate. Gushuling Granules were good uniform, damp-proofing, and formability, the critical relative humidity was 76%.Conclusion:
The preparation technology is stable. The study provides the experimental evidences for the research and development of Gushuling Granules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2014
Type:
Article
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