Chemical constituents from stems of Glycosmis pentaphylla / 中草药

ABSTRACT

Objective: To study the chemical constituents in the stems of Glycosmis pentaphylla. Methods: The constituents were isolated and purified by silica gel and preparative HPLC, and their structures were elucidated by means of physicochemical properties and spectroscopic analyses. Results: Nine compounds were isolated from the n-butanol-soluble fraction of 95% ethanol extract from the stems of G. pentaphylla, and identified as methyl 2-hydroxybenzoate 2-O-β-D-apiofuranosyl-(1→2)-O-β-D-glucopyranoside (1), inosine (2), 4-methoxy-8-(O-β-D-glucopyranosyloxy)-2(1H)-quinolinone (3), threo-guaiacyl-glycerol-8-O-4'-sinapyl ether 7-O-β-D-glucopyranoside (4), vitexin (5), ethyl-O-β-D-glucopyranoside (6), 2-propyl-O-β-D-glucopyranoside (7), threo-guaiacyl glycerol (8), and erythro-guaiacyl glycerol (9). Conclusion: Compound 1 is a new phenolic glycoside named glycopentosine A, and compounds 2-4 and 6-9 are isolated from the plants of Glycosmis Correa for the first time.