Chemical constituents from aerial part of fresh Euphorbia fischeriana / 中草药

ABSTRACT

Objective: To study the chemical constituents from the aerial part of fresh Euphorbia fischeriana. Methods: Fourteen compounds were isolated and purified by silica gel column chromatography, HPLC and recrystallization methods, and their structures were identified by spectral analysis. Results: Fourteen compounds were isolated and identified as 23 (E)-25-methoxycycloart-23-en-3β-ol (1), 24-hydroperoxycycloart-25-en-3β-ol (2), 25-hydro-peroxycycloart-23-en-3β-ol (3), lupeol (4), 24-methylenecycoartanol (5), euphol (6), 24-methylenecycloartane-3, 28-diol (7), obtusifoliol (8), phytol (9), jolkinolide A (10), 2, 4-dihydroxy-6-methoxy-3-methyl-1-acetophenone (11), 3-oxo-24-methylenecycloarane (12), 12-deoxyphorbol-13-hexadecanoate (13), and butyrospermol (14). Conclusion: Compound 9 is obtained from the plants in Euphorbia L. for the first time, and compounds 1-3 and 7-8 are isolated from E. fischeriana for the first time.