Study on purification of celandine extract from Tong'an Injection / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 2631-2635, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-854840
ABSTRACT
Objective:
To optimize the purification process of celandine in Celandine Alkali from Tong'an Injection, and to improve the content of celandine in Celandine Alkali extract.Methods:
In order to select the best way to separate celandine acid liquid, a study was carried out in three different ways of separation such as plate straight association-like centrifuge, high speed tubular centrifuge, and disc centrifuge; We investigated the dissolving effect caused by different pH values of hydrochloric acid to celandine dry extract; Three separation methods on celandine acidic lysate were investigated to choose the best, such as vacuum filtration, high-speed centrifuge tube, and flat direct-coupled centrifugal. Celandine Alkali transfer rate, and dry paste rate were as used evaluation indexes, so as to determine the feasible celandine refining purification process.Results:
It was the best way to separate celandine acid liquid by using disccentrifuge; Hydrochloric acid could have the best dissolving effect on celandine dry extract when the pH values were 3-4, and the transfer rate of chelidonine was also the highest; High-speed tubular centrifuge was the best separation method for the celandine acidic dissolution liquid.Conclusion:
The optimized process is simple, stable and viable, and it could be used for the preparation of qualified celandine intermediates.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2014
Type:
Article
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