Research progress on pharmacokinetics of cardiac glycosides / 中草药

ABSTRACT

Cardiac glycosides are proven to be effective in the clinical treatment for chronic heart failure and certain types of arrhythmia, especially for antitumor treatment. This paper focused on the research progress on pharmacokinetics of cardiac glycosides in recent years, elucidated the behaviors of absorption, distribution, metabolism, and excretion in vivo and in vitro, and summarized the metabolism of this kind of drug, aiming to provide an evidence for new drug research as well as a reference for the clinical safe use of these drugs.