Chemical constituents from Bidens bipinnata / 中草药

ABSTRACT

Objective: To study the chemical constituents from the herbs of Bidens bipinnata. Methods: The compounds were isolated and purified by various column chromatographies. Their structures were elucidated by means of physicochemical properties and spectral analyses (MS, 1H-NMR, and 13C-NMR). Results: Eighteen compounds were isolated from 95% ethanol extract of B. bipinnata and identified as quercetin-5-O-β-D-glucopyranoside (1), okanin-4′-O-β-D-(2″, 4″, 6″-triacetyl)-glucopyranoside (2), okanin-4′-O-β-D-(3″, 4″-diacetyl-6″-trans-p-coumaroyl)-glucopyranoside (3), luteolin-7-O-β-D-glucopyranoside (4), kaempferol-7-O-β-D-glucopyranoside (5), kaempferol-3-O-β-D-rutinoside (6), quercetin-3-O-β-D-glucopyranoside (7), quercetin-7-O-β-D-glucopyranoside (8), hyperoside (9), rutin (10), naringenin (11), apigenin (12), quercetin (13), 5, 7-dihydroxy chromone-7-O-β-D-glucoside (14), caffeic acid (15), gallic acid (16), β-sitosterol (17), and sitosterol-3-O-glucopyranoside (18). Conclusion: Compounds 1 and 11 are obtained from the plants in Bidens L. for the first time, and compounds 3-7, 14, 15, and 18 are firstly obtained from this plant.