Preparation and physicochemical properties of three kinds of superfine powder of Chinese materia medica / 中草药

ABSTRACT

Objective: To prepare the three kinds of superfine powder of Fritillariae Thunbergii Bulbus (FTB), Gastrodiae Radix (GR), and Rhodiolae Crenulateae Radix et Rhizoma (RCRR) and compare the differences of their physicochemical properties in different patical diameters of Chinese materia medica (CMM) powder. Methods: The superfine powder of FTB, GR, and RCRR was prepared to investigate the powder characteristics for the particle diameters, powder morphology, liquidity, and hygroscopicity. Furthermore, the ethanol extract and the effective ingredient content were quantified to evaluate the impact of particle diameters on the physicochemical properties of FTB, GR, and RCRR. Results: There were differences between the common and superfine powder in physicochemical characteristics. With the decreasing of particle diameters of FTB, GR, and RCRR powder, both the specific surface area and the moisture increased while the liquidity decreased slightly. The alcohol soluble extract and effective ingredient content increased. Conclusion: After superfine grinding, the powder properties of FTB, GR, and RCRR superfine powder are changed, the dissolution of effective ingredient is promoted, which provides the experimental references for the further study on the superfine powder of CMM.