Optimization of extracting technology for active fractions from Saxifraga stolonifera with anti-prostate cancer activity by response surface method / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 1768-1773, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-855253
ABSTRACT
Objective:
To optimize the extracting technology for active fractions from Saxifraga stolonifera with anti-prostate cancer activity.Methods:
Using the extraction rates of bergenin, quercetin-5-O-β-D-glucopyranoside, quercetin-3-O-L-rhamnopyranoside, quercetin, and flavonoids as indexes, the single factor experiment combined with Box-Behnken design was used to optimize the extracting technology.Results:
The optimal extraction conditions were as follows ethanol volume fraction 60.04%, liquid-solid ratio of 113.79 for 89.98 min, and at the temperature of 80°C. Under these conditions, the extraction rates of bergenin, quercetin-5-O-β-D-glucopyranoside, quercetin-3-O-L-rhamnopyranoside, quercetin, and flavonoids were 97.15%, 98.13%, 98.37%, 97.82%, and 96.33%, respectively.Conclusion:
The response surface analysis could optimize the extracting technology of active fraction from S. stolonifera with the anti-prostate cancer activity, which provides the basis for the comprehensive utilization and industrialization of S. stolonifera.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2013
Type:
Article
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