Chemical constituents from Iris scariosa and Iris halophila var. sogdiana / 中草药

ABSTRACT

Objective: To investigate the chemical constituents in the roots and rhizomes of Iris scariosa and Iris halophila var. sogdiana, respectively. Methods: The chemical constituents were isolated and purified by column chromatography (silica gel, ODS, Sephadex LH-20, and macroporous resin HP-20) and RP-preparative TLC. Their structures were identified by spectroscopic methods (MS, 1H-NMR, 13C-NMR, and 2D-NMR). Results: Six compounds, irigenin (1), nigricin-4'-[O-β-D-glucopyranosyl-(1‴→6″) - β-D-glucopyranoside] (2), 5, 7, 2'-trihydroxy-6-methoxy-flavanone (3), nigricin (4), irilone (5), and iriflophenone (6) were isolated and identified from the roots and rhizomes of I. scariosa. Besides, seven compounds, 5, 7, 2'-trihydroxy-6-methoxy-flavanone (3), irilin A (7), iristectorigenin B (8), iristectorigenin B 4'-O-β-D-glucopyranoside (9), iristectorigenin B 4'-[O-β-D-glucopyranosyl-(1‴→6″) - β-D-glucopyranoside (10), alpinone (11), and β-daucosterol (12) were isolated and identified from the roots and rhizomes of I. halophila var. sogdiana. Conclusion: Compound 9 is a new one named halophiloside. Compounds 1-6 are isolated from I. scariosa and compounds 3 and 7-12 are isolated from I. halophila var. sogdiana for the first time, respectively.