Chemical constituents from berries of Physalis pubescens / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the berries of Physalis pubescens. Methods: The chemical constituents were isolated by repeated silica gel column chromatography, Sephadex LH-20 gel columns chromatography, medium pressure column chromatography, and semi-preparative liquid chromatography, and their structures were elucidated by chemical properties and spectral analyses. Results: Sixteen compounds were isolated and identified to be 3, 7, 3'-trimethylquercetin (1), kaempferol (2), chrysoeriol (3), quercetin-3-O-β-D-glucopyranoside (4), arjunolic acid (5), pulsatilla saponin A (6), pulsatilla saponin D (7), caffeic acid (8), 1-O-caffeoyl-β-D-glucopyranoside (9), N-trans-ferulogltyramine (10), neo-olivil (11), medioresinol (12), pinoresinol (13), sucrose (14), uridine (15), and β-sitosterol (16). Conclusion: Compounds 5-7 and 9-15 are obtained from the plants of genus Physalis L. for the first time. Compounds 3 and 8 are obtained from this plant for the first time.