Comparison of Histologic Changes According to Treatment Method in Experimentally Perforated Rabbit Eyes

ABSTRACT

Perforation of the choroid and retina during strabismus surgery is fairly common and optimal management of global perforation is contoversial. The authorsinvestigated the histological changes of the rabbit eyes to compare the treatment effects of diode laser photocoagulation, cryotreatment, and nontreatment in experimentally perforated rabbit eyes.We perforated the globe of 6 pigmented rabbits (12 eyes)and treated four eyes with diode laser and four with cryotherapy and did not treat the remaining four.Proliferation of stromal cells and chorioretinal adhesion were seen in untreated eyes. The cryotherapy eyes revealed retinal destruction and pigment-laden cells in all retinal layers.The eyes treated by diode laser showed firm chorioretinal adhesion and relatively well preserved inner layers of retina.We concluded that directed diode laser photocoagulation was a safe and effective method of retinopexy to prevent the retinal detachment after globe perforation durng strabismus surgery.