Chemical constituents of Lobelia chinensis / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 794-797, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-855400
ABSTRACT
Objective:
To investigate the chemical constituents in the dried whole plant of Lobelia chinensis.Methods:
Column chromatography, such as silica gel, MCI, ODS, Sephadex LH-20, C18 reverse-phased silica gel columns, and preparative HPLC were used to isolate the compounds. Spectroscopic methods like MS, 1H-NMR, and 13C-NMR were used to elucidate their structures.Results:
Fifteen compounds were isolated from 95% ethanol extract of L. chinensis, including twelve flavonoids quercetin (1), rutin (2), luteolin (3), apigenin (4), hesperidin (5), quercetin-3-O-α-L-rhamnoside (6), quercetin-7-O-α-L-rhamnoside (7), quercetin-3- O-β-D-glucoside (8), amentoflavone (9), naringenin (10), hesperetin (11), and eupafolin (12), and three coumarins 5, 7- dimethoxy-coumarin (13), isoscopoletin (14), and scoparone (15).Conclusion:
Compounds 6-12 are isolated from the plants in genus Lobelia L. for the first time. Compounds 5, 13, and 14 are isolated from L. chinensis for the first time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2013
Type:
Article
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