Chemical constituents from barks of Pterocarya stenoptera / 中草药

ABSTRACT

Objective: To study the chemical constituents in the barks of Pterocarya stenoptera. Methods: The chemical constituents in chloroform and ethyl acetate fractions of 90% ethanol extract from the barks of P. stenoptera were isolated and purified by column chromatography over silica gel, ODS, Sephadex LH-20 columns, preparative HPLC, and recrystallization. The structures of the isolated compounds were identified on the basis of physicochemical properties and spectral data analyses. Results: Fourteen compounds were obtained and identified as glochidone (1), lup-20(29)-en-1β, 3β-diol (2), ursolic acid (3), betulinic acid (4), 2α, 3β, 19α-trihydroxyurs-12-en-28-O-β-D-glucopyranoside (5), (4S)-4, 8-dihydroxy-1-tetralone (6), 5-hydroxy-4-methoxy-α-tetralone (7), (4S)-4-hydroxy-1-tetralone (8), myricitrin (9), 30-norlupan-28-oic acid (10), myrictin (11), quercetin-3-O-2″-galloyl-rhamnoside (12), oleanolic acid (13), and 3, 3'-di-O-methyl ellagic acid-4'-O-β-D-xylopyranoside (14). Conclusion: Compounds 1-14 are isolated from the plant for the first time, and compounds 5 and 7-14 are obtained from the plants in Pterocarya Kunth. for the first time.