Extraction, isolation, and structure elucidation of two new triterpene glycosides from sea cucumber Holothuria nobilis / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 1467-1472, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-855548
ABSTRACT
Objective:
To study the constituents from the sea cucumber Holothuria nobilis.Methods:
The compounds of the sea cucumber were separated by multi-chromatography and their structures were elucidated by physico-chemical and spectral analyses.Results:
Two new triterpene glycosides were isolated and their structures have been deduced by extensive spectral analysis (IR, 2D-NMR, and ESI-MS) and chemical structures as 3-O-{3″″-O-methyl-β-D- glucopyranosyl-(1→3)-β-D-glucopyranosyl-(1→4)-β-D- quinovopyranosyl-(1→2)-4′-O-sulfate-β-D-xylopyranosyl} -holosta-22, 25-epoxy-9-ene-3β, 12α, 17α, 25β-tetraol- sodium salt (nobiliside I, 1) and 3-O-{β-D-quinovopyranosyl-(1→2) 4′-O-sulfate-β-D-xylopyranosyl}-holoshillaside 18 (16)-lactone-22, 25-epoxy-9-ene-3β, 12α, 17α-triol sodium (nobiliside II, 2).Conclusion:
Two aglycons are both new compounds named nobiliside I and nobiliside II.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
2011
Type:
Article
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