Chemical constituents from Osbeckia chinensis / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from Osbeckia chinensis. Methods: The constituents were separated by column chromatography and their structures were elucidated by spectral data analyses. Results Sixteen compounds were isolated from O. chinensis and identified as 4-0-β-D- glucopyranosyl-3-O-methylellagic acid (1), 4-O-β-D-glucopyranosyl-3, 3′-di-O-methylellagic acid (2), 4-O-β-D-glucopyranosyl-3,3′, 4′-tri-O-methylellagic acid (3), kaempferol-3-O-β-L-ramnopyranoside (4), quercetin-3-O-β-D-galactopyranoside (5), quercetin-3-O-β-D- rhamnopyranoside (6), kaempferol-6-C-β-D-glucopyranoside (7), quercetin-3-O-β-D-rhamnopyranosyl-2″-acetyl (8), kaempferol-3-O- β-D-glucopyranosyl-2″,6″-bis-O-E-(4-hydroxy)-cinnamoyl (9) 4′-hydroxyflavone-3-O-(6-O-trans-p-coumaroyl)-β-D-glucopyranoside (10), kaempferol-3-O-β-D-glucopyranosyl-6‴-O-E-(4-hydroxy)-cinnamoyl (11), 3β-hydroxy-9(11)-fernen-23-oic acid (12), 1,2-dihydroxy-9(11)- arborinen-3-one (13), cholest-5-ene-2,3,21-triol (14), β-sitosterol (15), and daucosterol (16). Conclusion: Except for compounds 5 and 16, all compounds are obtained from O. chinensis for the first time.