Chemical constituents of Mangifera indica leaves (I) / 中草药

ABSTRACT

Objective: To study the chemical constituents of Mangifera indica leaves. Methods: Silica gel, ODS, Sephadex LH-20 column chromatography, and HPLC were used to isolate and purify the constituents, and their structures were identified by physicochemical properties and spectral data. Results: Eleven compounds were isolated from 70% ethanol extract, and identified as quercetin-3-O-β-L-rhamnopyranoside (1), hyperin (2), quercetin-3-O-β- glucopyranoside (3), 7-O-methylquercetin-3-O-β-L-rhamnopyranoside (4), rhamnetin-3-O-β-D-glucopyranoside (5), amentoflavone (6), mangiferin (7), irisflophenone-3-C-β-glucoside (8), maclurin-3-C-β-glucoside (9), 2,4′,6-trihydroxy-4-methoxybenzophenone-2-O-β-glucoside (10), and irisflophenone-3-C-(6-O-p-hydroxybenzoyl)-O-β-glucoside (11), respectively. Conclusion: Compounds 4 and 10 are obtained from the plants of Mangifera L. for the first time, and the NMR data of compound 11 is reported for the first time.