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Two new triterpene glycosides from Stichopus variegatus / 中草药
Chinese Traditional and Herbal Drugs ; (24): 10-14, 2011.
Article in Chinese | WPRIM | ID: wpr-855694
ABSTRACT

Objective:

To study the constituents from the sea cucumber, Stichopus variegatus.

Methods:

The crude saponins of S. variegatus were desulfated with pyridine-dioxane (11), the desulfated products were separated by multi-chromatography to afford two compounds.

Results:

On the basis of chemical methods and spectral evidences, especially 2D-NMR and ESI-MS, these two compounds were identified as 3-0-[β-D-xylopyranosyl-(1→2)-4′-O- sulfate-β-D-xylopyranosyl]-holosta-9-ene-3β,12α,17α, 25β-tetraol sodium salt, named as variegatuside A (1) and 16β-acetoxy-3-O-β-D-xylopyranosyl-holosta-22,25-epoxy-9-ene-3β, 12α,17α-triol, named as variegatuside B (2).

Conclusion:

Compounds 1 and 2 are new compounds.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Traditional and Herbal Drugs Year: 2011 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Traditional and Herbal Drugs Year: 2011 Type: Article