Analysis of risk factors for recurrent intracerebral hemorrhage / 中国脑血管病杂志

ABSTRACT

Objective: To investigate the related factors of recurrent intracerebral hemorrhage in patients with intracerebral hemorrhage in order to provide references for prevention and treatment. Methods: The clinical data of recurrent intracerebral hemorrhage in 3672 patients with intracerebral hemorrhage were analyzed retrospectively. They were divided into recurrent intracerebral hemorrhage group (n = 239) and first attack of intracerebral hemorrhage group (n = 3433). The univariate analysis was performed first, and the risk factors with significant statistical difference were screened, and then a multivariate logistic regression analysis was used to determine the independent risk factors for recurrent intracerebral hemorrhage. Results: Circled digit one The incidence of recurrent intracerebral hemorrhage in 3672 patients was 6.51% (239/3672) and the mortality of recurrent intracerebral hemorrhage was 19.25% (46/239). Circled digit twoThe univariate analysis showed that recurrent intracerebral hemorrhage was associated with hypertension, taking anti-platelet aggregation agents, diabetes mellitus, long history of smoking, and alcoholism. The proportions of patients with history of diabetes mellitus, long history of smoking, oral take of anticoagulants, systolic blood pressure and diastolic blood pressure in the recurrent intracerebral hemorrhage group were significantly higher than those in the first attack of intracerebral hemorrhage group. Among the sites of bleeding, the basal ganglia region was higher, and the age of patients were older (all P < 0.01). Circled digit threeA multivariate stepwise logistic regression analysis revealed that the mean diastolic blood pressure (OR = 8.7893, 95% CI 5.0162-18.9358), use of anticoagulants (OR = 3.7273,95% CI 1 8245-5.7806), long history of smoking (OR = 3.1654, 95% CI 1.6124-5.4528), high systolic blood pressure (OR = 2.9463, 95% CI 1.4596 -4.9753), and diabetes mellitus (OR = 2.4689, 95%, CI 1.1807-4.7650) were the independent risk factors for patients with recurrent intracerebral hemorrhage. Conclusion: Recurrent cerebral hemorrhage in patients with cerebral hemorrhage is correlated with the higher diastolic blood pressure, use of anticoagulants, long history of smoking, higher systolic blood pressure, and diabetes mellitus.