A novel liquid embolic agent Onyx in the treatment of intracranial aneurysms: Preliminary experience / 中国脑血管病杂志
Chinese Journal of Cerebrovascular Diseases
;
(12): 110-113, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-856199
ABSTRACT
Objective:
To explore the therapeutic effect of Onyx (an embolic agent) in the embolization of intracranial aneurysms.Methods:
16 patients with intracranial aneurysms were treated endovascularly, 5 patients with small aneurysms (2 with a narrow-neck, 3 with a wide-neck), and 11 patients with large or giant intracranial aneurysms (all with wide-neck). One patient with large aneurysm recanalized after coiling, and was retreated with Onyx, and the remaining 15 patients were treated with Onyx only. The follow-up time was 6 months to 2 years by letters or digital subtraction angiography (DSA) after the procedures.Results:
All the 5 small aneurysms were 100% occluded; of 11 large or giant aneurysms, 7 aneurysms were 100% occluded and 4 aneurysms were 95% occluded. All their parent arteries remained patent. Three patients had procedure-related complications 1 patient had ipsilateral intracerebral hematoma immediately after the procedure; and 1 patient with the internal carotid-cavernous sinus aneurysm whose oculomotor paralysis worsened after the procedure; another with internal carotid-posterior communicating artery aneurysm had contralateral hemiparesis. The procedure-related morbidity and mortality were 12% and 6%, respectively. Six patients were followed up by DSA, 2 small aneurysms and 1 large aneurysm did not recur, 3 giant aneurysms recurred. The 9 remaining patients were followed-up by letters. Eight patients no new symptom occurred and one died of unknown cause.Conclusion:
Both short- and long-term efficacy of Onyx for small wide-necked aneurysms is good, and the short-term efficacy for large and giant wide-necked aneurysms is satisfactory.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Cerebrovascular Diseases
Year:
2006
Type:
Article
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