Research progress of serca2a in heart failure / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 171-174, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-857012
ABSTRACT
Heart failure from various cardiovascular diseases is a serious threat to human health. Systolic and diastolic dysfunction are the basic characteristics of heart failure. SERCA2a, a key enzyme for calcium transport, regulates intracellular free calcium ion concentration, affecting the myocardial diastolic process. This article mainly summarized the structure and function of SERCA2a gene, the expression and regulation of SERCA2a in heart failure, and the current situation of drug therapy, gene therapy and clinical research targeting SERCA2a gene.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2020
Type:
Article
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