Advances in research on notch signaling pathway in pulmonary vascular remodeling of pulmonary arterial hypertension / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 5-8, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-857034
ABSTRACT
Pulmonary hypertension is a cardiovascular disease characterized by persistent elevation of pulmonary artery pressure and pulmonary vascular resistance, causing pulmonary vascular remodeling. Notch signaling pathway is a highly conserved signaling pathway involved in the occurrence and development of cardiovascular, neurological and tumor diseases mainly by regu-lating cell proliferation, differentiation and apoptosis. TTiis paper mainly reviews the molecular mechanism of Notch signaling path way involved in pulmonary vascular remodeling, contributing to provide a new strategy for the treatment of pulmonary arterial hypertension.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2020
Type:
Article
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