Protective effects of total saponins of tribulus on cerebral ischemia reperfusion injury in rats / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 111-114, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-857406
ABSTRACT
Aim:
To observe the protective effects of total saponins of tribulus (TST) on cerebral ischemia reperfusion injury in rats.Methods:
Rat cerebral ischemia-reperfusion injury was induced by middle cerebral artery occlusion . The neurological outcome was evaluated. CK, LDH and NO activity in serum, SOD and MDA levels of cerebral tissue were measured.Results:
The levels of CK, LDH, NO, SOD and MDA in TST(30 mg·kg-1, 10 mg·kg -1) groups were significantly lower than those in model group. The level of cellular and intercellular edema was reduced markly in the pathomorphology examination. The neurological deficits was decreased by TST.Conclusion:
TST has protective effects on cerebral ischemia reperfusion injury in rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2005
Type:
Article
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