Your browser doesn't support javascript.
loading
Quality Comparison of Jinyinhua Formula Granules from Different Enterprises Using HPLC Fingerprint / 中国药学杂志
Chinese Pharmaceutical Journal ; (24): 631-636, 2020.
Article in Chinese | WPRIM | ID: wpr-857732
ABSTRACT

OBJECTIVE:

To establish the HPLC fingerprint of Jinyinhua formula granules (JYHFG), and compare the qualities of the products from nine enterprises by chemical metrology analysis.

METHODS:

HPLC was used to establish fingerprint at 254 nm. Twenty-nine batches of products from nine enterprises were determined, and the quality of JYHFG of different batches was evaluated through similarity evaluation, clustering analysis (HCA) and principal component analysis (PCA).

RESULTS:

Seventeen common peaks were confirmed in the HPLC fingerprint of 29 batches of JYHFG, and 10 of them were identified. The similarity of JYHFG was 0.84-0.99, and the samples could be grouped into one category according to enterprise, among which the characteristic peak of chlorogenic acid had the greatest influence on the fingerprint.

CONCLUSION:

The establishment of HPLC fingerprint and the identification of chemical pattern provide a more comprehensive reference for the quality control of JYHFG. It provides a reliable method for scientific evaluation and effective quality control.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Pharmaceutical Journal Year: 2020 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Pharmaceutical Journal Year: 2020 Type: Article