Adulteration situation of ophiopogonis radix in niuhuang qingwei pills / 中国药学杂志

ABSTRACT

OBJECTIVE: To establish the detection method of Liriopes Radix in Niuhuang Qingwei pills to uncover the adulteration situation of Ophiopogonis Radix in Niuhuang Qingwei pills. METHODS: Liriopesides B and liriope muscari baily saponins C in Niuhuang Qingwei pills were analyzed by HPLC-MS-MS in MRM mode. RESULTS： In the 18 batches of Niuhuang Qingwei pills, liriopesides B and liriope muscari baily saponins C, the index compounds of Liriopes Radix, were detected in 15 batches of samples in the concentrations of 0.10-1.19 μg·g-1. CONCLUSION： The adulteration of Ophiopogonis Radix with Liriopes Radix should be paid more attention to.