Chemical Comparison of the Stems and Leaves of Tussilago farfara L. Using NMR-based Metabolomics / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 608-613, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-858026
ABSTRACT
OBJECTIVE:
To compare the chemical compositions of the stems (STL) and leaves (LTL) of Tussilago farfara L. using NMR-based metabolomic approach.METHODS:
The STL and LTL were analyzed by NMR, then the differential components were determined by multivariate statisticalMETHODS:
, including PCA, PLS-DA, OPLS-DA, and univariate analysis.RESULTS:
Fifty compounds were tentatively identified in the NMR spectra of STL and LTL. Multivariate coupled with univariate analysis revealed that some metabolites, such as valine,leucine,isoleucine,proline,chlorogenic acid,3,5-O-dicaffeoylquinic acid, 3,4-O-dicaffeoylquinic acid, and tussilagone,were present at higher levels in the LTF, while the STF contained higher levels of α-glucose and β-glucose.For some metabolites, such as malic acid, sucrose and choline, no significant differences were observed between STF and LTF.CONCLUSION:
This study reveals the chemical differences between STF and LTF in a holistic way, and lays the scientific foundation for the resource utilization of the stems and leaves of T. farfara L.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2019
Type:
Article
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