Chemical Constituents from Rhizoma Zingiberis / 中国药学杂志

ABSTRACT

OBJECTIVE To study the chemical constituents of Rhizoma Zingiberis. METHODS: Diaion HP-20, Toyopearl HW-40, ODS, silica gel column and semi-preparation liquid were used to separate and purify the structure, and the structure was identified according to the physical and chemical properties and spectral data of the compound. RESULTS: Fifteen compounds were isolated and identified from Rhizoma Zingiberis, which were renealtin A(1),kravanhol A(2),1, 7-bis(3,4-di-hydroxyphenyl)-3-heptanone(3),dihydrocannabinone C(4), 1, 7-bis(3, 2), 1, 7-bis(3,4-di-hydroxyphenyl) 4-dihydroxyphenyl) heptane-3-ylacetate(5),(5R)-1,7-bis(3, 4-dihydroxy)-3-hydroxyphenylheptane(6), citrus acid(7), citrate 4-(1-methoxyethyl)-phenol(8), 3-indolecarboxy(9), 3, 4-dimethoxyphenylacetic acid(10),(2E,6E)-2,6-dimethylocta-2, 6-dienedioicacid(11), cyclo-(D-Leu-L-Trp)(12), cyclo-(S-Pro-S-Phe)(13), 8-hydroxygeraniol(14) and (Z)-2, 6-dimethyloct-6-ene-1, 8-dihydroxy(15). CONCLUSION: Compounds 1-15 were isolated from the plant for the first time.