Progress on Pharmacodynamic Material Basic of Traditional Chinese Medicine / 中国药学杂志

ABSTRACT

Traditional Chinese medicine(TCM) has the characteristics and complexities of multi-component, multi-target and multi-way. The study of TCM compound efficacy material basis is the core part in illuminating the effect and mechanism of TCM. So many methods were involved in the researches on material foundation including the effective part searching, compatibility and its disassembled prescriptions investigating based on pharmacological activity tracking in vivo; the association analysis between chemical fingerprints characterized by a variety of instruments and efficacy; serum pharmacochemistry and Chinmedomics based on metabolic processes in vivo; cell membrane chromatography and bionic technology based on activity discovering in vitro; and network pharmacology based on the computer simulation. The paper summarized the research methods in this field by consulting and concluding some document data of recent years, aiming to provide a theoretical foundation for studying on the effective material foundation of compound prescription of traditional Chinese medicine.