The Research Progress in Lyoprotectants of Protein and Its Protection Mechanism / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 765-770, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-858326
ABSTRACT
At present, freeze-drying is an important means for manufacturing and storing protein pharmaceutical products. Lyoprotectants are the excipients to maintain the protein stability during freeze-drying and storing. In this review, the effects of lyoprotectants on protein drugs, the protection mechanism, the research progress and the selection of lyoprotectants are summarized through consulting the literatures in recent years. We can find that searching for stable and efficient protein lyoprotectants and their formulations is the hotspot.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2018
Type:
Article
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