Electrochemical Detection in High Performance Liquid Chromatography for Analysis of Pharmaceutical Drugs / 中国药学杂志

ABSTRACT

High performance liquid chromatography-electrochemical detection (HPLC-ED)is an important analytical tool for the determination of pharmaceutical drugs since electrochemical detectors provides derivertization-free, sensitive, selective, and low cost detection methods. Numerous papers and reviews have been published since the HPLC-ED techniques were introduced forty years ago. This article will review the electrochemical instruments and detection methods used in HPLC, and focus on recent advances in the analysis of pharmaceutical drugs using HPLC-ED techniques, and discuss the future development trend of the techniques.