Isolation and Identification of Gingerols Constituents from Zingiber officinale Rosc / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Zingiber officinale Rosc. METHODS: Various column chromatographic techniques were used to isolate and purify the chemical constituents and their structure were elucidated by spectral analysis. RESULTS: Ten compounds were isolated and identified as 6-shogoal (I), 9-shogoal (II), 10-shogoal (III), 12-paradol (IV), 6-gingerol (V), 6-isodehydrogingerdione (VI), 8-isodehydrogingerdione (VII), 5-hydroxy-1-(4'-hydroxy-3'-methoxyphenyl)-4-hexa-decen-3-one (VIII), (E)-geranylferulic acid (IX), and 5-ethoxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one (X). CONCLUSION: The compounds II, III, IV, VI, VII and X are isolated from Zingiberis Rhizoma for the first time.