Chemical Constituents in N-butanol Extracts from Yao Medicine Pileostegia tomentella / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Yao medicine, Zhongliuteng, the stems of Pileostegia tomentella. METHODS: The chemical constituents were isolated and purified by silica gel chromatography repeatedly, and their structures were identified by spectral analysis and chemical METHODS. RESULTS: Thirteen compounds were isolated from the stems of P. tomentella and the structures were identified as 1-O-(β-D-glucosyl)-2-[2-methoxy-4-(ω-hydroxypropyl) phenoxy]propan-3-ol(1), (+)-lyoniresinol-3a-O-β-D-glucopyranoside (2), syringin (3), coniferin (4), dihydroconiferin (5), but-3-enyl-β-D-glucoside (6), 4-(2, 3-dihydroxypropyl)-2, 6-dimethoxy phenyl β-D-glucopyranoside (7), nikoenoside (8), protocatechuic acid ethyl ester (9), 8-methoxy coumarin-7-O-β-D-glucopyranoside (10), 6-O-R-L-rhamnopyranosyl-β-D-glucopyranoside methyl salicylate (11), nicotinamide (12), and 3, 5-di-O-caffeoyl quinicacid methyl ester (13). CONCLUSION: All compounds were obtained from the genus for the first time.