Summary and Analysis of Clinical Practice Guidelines for Proton Pump Inhibitors in China / 中国药学杂志

ABSTRACT

OBJECTIVE: To know about the application of proton pump inhibitors (PPI)in different diseases and provide the essential references for the use of PPI, clinical practice guidelines for PPI in China were sort out and analyzed. METHODS: The clinical practice guidelines of PPI were searched and sort out according to the categories, levels of evidence of effectiveness and safety, strength of recommendations of guidelines, and so on. RESULTS: Seventeen clinical practice guidelines, which are related to the prevention and cure in gastrointestinal disease, were included in our researches. Except five guidelines, the rest of them were not evidence-based clinical guidelines. CONCLUSION: The recommendations of the clinical practice guideline for PPI are not just very clear, which lead to disorder of PPI clinical medication, the urgent need is to develop relevant provisions to further regulate the PPI medication.