A Case of Acute Hepatitis B by Occult HBV Infection without HbsAg Seroconversion / 대한내과학회지
Korean Journal of Medicine
; : 619-623, 2012.
Article
in Ko
| WPRIM
| ID: wpr-85860
Responsible library:
WPRO
ABSTRACT
Many studies have recently reported reactivation in hepatitis B surface antigen (HBsAg)-negative subjects with the use of biologic agents such as rituximab. However, occult hepatitis B virus infection itself has little clinical impact. We experienced a case of acute exacerbation caused by occult hepatitis B infection without HBsAg seroconversion. No mutation was found on the major hydrophilic loop of the S protein. The patient recovered from acute exacerbation after antiviral therapy. In conclusion, acute exacerbation can be induced by occult hepatitis B virus infection itself without reactivation. In such a case, antiviral therapy should be considered.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Hepatitis B virus
/
Antibodies, Monoclonal, Murine-Derived
/
Rituximab
/
Hepatitis
/
Hepatitis B
/
Hepatitis B Surface Antigens
Limits:
Humans
Language:
Ko
Journal:
Korean Journal of Medicine
Year:
2012
Type:
Article