Chemical constituents from asplenium unilaterale / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents from the whole plants of Asplenium unilaterale. METHODS: The methanol extract was isolated and purified by silica gel, Sephadex LH-20, and semi-preparative HPLC column chromatography. All compounds were identified on the basis of spectral analysis. RESULTS: Fifteen compounds were isolated and identified as (Z)-4-(2, 6, 6-trimethylcyclohex-2-enylidene) butan-2-ol (1), icariside B2 (2), citroside A(3), (6R, 9R)-3-oxo-α-ionol-9-O-β-D-glucopyranoside(4), (6S, 9R)-roseoside(5), 6-methyl-2H-chromen-2-one (6), 6, 7-dihydroxy-2H-1-benzopyran-2-one (7), gibepyrone D(8), lupan-3-one(9), violanthin(10), 22, 23-dimethylcholest-5-en-3-ol(11), 1-dotriacontanol (12), 5-hexylfuran-2(5H)-one(13), tocopherylquinone( 14) and 2, 4 (1H, 3H)-pyrimidinedione(15), respectively. CONCLUSION: Compounds 1-15 are isolated from the genus for the first time.