Isolation and identification of the chemical constituents from cortex of african traditional medicinal Pausinystaliamacroceras P / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents from cortex of African traditional medicine Pausinystalia macroceras P. METHQDS Various column chromatographic techniques were used to isolate and purify the chemical constituents and their structures were elucidated by spectral analysis and chemical analysis. RESULTS: Nine compounds were isolated and identified as corynan-theidine(I), corynantheine(II), ajmalicine(III), yohimbine(IV), corynanthine(V), α-yohimbine(VI), α-yohimbine(VII), β-sitosterol(VI), ursolic acid(IX) and oleanolic acid(X). CONCLUSION: The compounds I, IV, VIII, IX and X are isolated from Pausinystalia macroceras P. for the first time.