Phenotypes and endotypes of severe asthma in children / 소아과
Korean Journal of Pediatrics
;
: 191-195, 2013.
Article
in English
| WPRIM
| ID: wpr-85907
ABSTRACT
Severe childhood asthma is a complicated and heterogeneous disorder with distinct phenotypes. Children with severe asthma have more persistent symptoms despite receiving treatment, more atopy, greater airway obstruction, and more air trapping than those with mild-to-moderate asthma. They also have higher morbidity and substantial airflow limitations that persist throughout adulthood. Identification of the phenotype clusters and endotypes of severe asthma can allow further modulation of the natural history of severe asthma and may provide the pathophysiologic rationale for appropriate management strategies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Asthma
/
Natural History
/
Airway Obstruction
Limits:
Child
/
Humans
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2013
Type:
Article
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