Saxagliptin in treatment of type 2 diabetes mellitus: A systematic review of pharmacoeconomic studies / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 1044-1048, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-859084
ABSTRACT
OBJECTIVE:
To systematically evaluate the economics of saxagliptin for treatment of type 2 diabetes mellitus.METHODS:
PubMed, Embase, Cochrane Library, NHS EED, CNKI, Wanfang and CBM were systematically searched. Literatures were screened according to pre-defined inclusion criteria. The quality of included studies were evaluated by CHEERS statement and the economic results were systematically analyzed.RESULTS:
Eight cost-effectiveness analyses were included, one of which was conducted in China. Patients among the studies all had blood glucose non-adeguately controlled by monotherapy. When added on to metformin, saxagliptin was cost-effective compared with sulfonylureas (glipizide and glimepiride) and thiazolidinediones (pioglitazone and rosiglitazone). When added on to metformin or sulfonylureas, saxagliptin was cost-effective compared with NPH insulin.CONCLUSION:
Saxagliptin represents a cost-effective option in treatment of type 2 diabetes mellitus patients with non-adequately controlled blood glucose after monotherapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Systematic reviews
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2016
Type:
Article
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