Identification of compounds in alien invasive plant Chromolaena odorata / 中国药学杂志

ABSTRACT

OBJECTIVE: To investigate the chemical constituents from Chromolaena odorata (L.) as an invasive plant. METHODS: Colum chromatography with different materials was used to isolate and purify the chemical constituents. Their structures were identified by spectroscopic analysis. RESULTS: Seventeen compounds were obtained, including 15 flavonoids, one sesquiterpene, and one steroid, and identified as persicogenin(1), naringenin-7, 4'-dimethyl ether(2), quercetin-7, 4'-dimethylether(3), odoratin(4), stigmasterol(5), 6-hydroxyl-5, 7, 4'-trimethoxyflavone(6), 4, 2'-dihydroxy4', 5', 6'-trimethoxychalcone(7), dihydrokaempferide (8), 3, 5, 4'-trihydroxy-7, 3'-dimethoxyflavanone(9), 5, 6, 7, 3', 4'-pentamethoxyflavone(10), 5, 7, 3', 4'-tetramethoxyflavanone(11), radicol(12), 5, 7-dihydroxy-6, 4'-dimethoxy dihydroflavone(13), 4'-methoxydihydroquercetin(14), 4'-hydroxy-5, 6, 7-trimethoxyflavanone(15), 4'-hydroxy-5, 6, 7, 3'-tetramethoxyflavone(16), and 3', 4-dihydroxy-5, 6, 7-trimethoxyflavone(17). CONCLUSION: Compounds 6, 9, 11-12, 14, and 16 are obtained from this plant for the first time. Compounds 12 and 14 are obtained from Chromolaena genus for the first time.