Research development of prodrugs triggered by colon bacteria-releasing enzymes on colon-targeted treatment / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 1-6, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-859325
ABSTRACT
By researching the relevant papers at home and abroad, the principles of preparation, drug release mechanism, existing problems and so on were analysed and summarized on prodrugs triggered by colon bacteria-releasing enzymes (PTCBE). Compared with ordinary drugs, PTCBE was degraded by colon bacteria-releasing enzymes on colon-targeted treatment. PTCBE have the drug release characters of specificity, accuracy and so on for the colon-targeted treatment and can reduce the adverse drug reactions. Thus PTCBE have the good prospects of applications.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2015
Type:
Article
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