Utilization of proton pump inhibitors in six areas in China / 中国药学杂志

ABSTRACT

OBJECTIVE: To investigate the rationality and trend of utilization of proton pump inhibitors (PPIs) in six areas in China in 2011-2013. METHODS: The utilization of PPIs in Beijing, Chengdu, Guangzhou, Shanghai, Tianjin, and Hangzhou during the period of 2011-2013 were analyzed statistically in respect of consumption sum, DDDs, AARG, DDC, drug interactions, and medical insurance categary. RESULTS: Both the consumption sum and DDDs of PPIs increased quickly in the recent three years. The amount of omeprazole was the greatest and increased steadily. The amounts of rabeprazole and lansoprazole also increased rapidly especially for the domestic products. Medical insurance categary had no obvious effect on clinical choice. PPIs became more cheaper for patients. Rabeprazole and pantoprazole were preferred when PPIs were combined with other drugs, especially in the hospitals which had clinical pharmacist working in the department of gastroenterology or cardiology. CONCLUSION: The use of PPIs tends to be more rational, in which clinical pharmacists play a very important role.