Analysis of difference in chemical constituents of Radix Pseudostellariae from different germplasms by UPLC-Triple TOF-MS/MS / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 1104-1110, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-859521
ABSTRACT
OBJECTIVE:
To analyze the differences in chemical composition of Pseudostellariae Radix from different germplasms.METHODS:
Tweny-four batches of samples were determined by UPLC-Triple TOF-MS/MS. Characteristic peaks were extracted through treatment of mass spectrometry data including peak matching, peak alignment and noise filtering. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) were used for data processing. Component identification was carried out based on the mass spectrometry accurate mass and secondary mass spectrometry fragmentation information combined with database search and literature.RESULTS:
The differences among samples of Pseudostellariae Radix of different germplasms were distinguishable. Twenty-one chemical compositions with significant differences were screened, among which 10 common chemical compositions showed different changing laws.CONCLUSION:
This study provides experimental data for revealing the laws of Pseudostellariae Radix metabolites from different germplasms.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2015
Type:
Article
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