Chemical constituents of roots of Astragalus membranaceus (Fisch) Bge. var. mongholicus (Bge) Hsiao / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of roots of Astragalus membranaceus (Fisch) Bge. var. mongholicus (Bge) Hsiao. METHODS: The chemical constituents of Astragalus membranaceus (Fisch) Bge. var. mongholicus (Bge) Hsiao were isolated and purified by D101 column chromatography and preparation HPLC. Their structures were identified by physicochemical properties and spectral analysis methods. RESULTS: Seven compounds were obtained and identified as 4, 4′-dimethyl-6′-hydroxychalcone (1), 4-methoxy-4′, 6′-dihydroxychalcone(2), 7, 4′-dihydroxyflavonone(3), 4, 4′, 6′-trihydroxychalcone(4), 4′-hydroxyflavonone-7-O-β-D-glucoside(5), 2′-hydroxy-3′, 4′-dimethylisoflavan-7-O-β-Z)-glucoside(6), and 3, 2′-dihydroxy-3′, 4′-dimethylisoflavan-7-O-β-D-glucoside (7). CONCLUSION: All these compounds were isolated from this plant for the first time.