Risk Factors Influencing Decline of Residual Renal Function in Patients on Continuous Ambulatory Peritoneal Dialysis / 대한신장학회지
Korean Journal of Nephrology
;
: 752-760, 2010.
Article
in Korean
| WPRIM
| ID: wpr-85988
ABSTRACT
PURPOSE:
Preservation of residual renal function (RRF) after initiation of peritoneal dialysis (PD) is beneficial for patient survival. It is unclear that same risk factors of pre-dialysis chronic kidney disease (CKD) patients affect RRF in PD patients. This study was aimed to evaluate factors affecting RRF after commencement of PD.METHODS:
Data from 80 patients commencing CAPD at Kyungpook National University Hospital between January 2001 and December 2008 were retrospectively collected. After PD commencement, biochemical and clinical data at baseline (1 month), 6, and 12 month were obtained. RRF was calculated as the average of creatinine clearance and urea nitrogen clearance from 24-hour urine collection and normalized with body surface area and mean RRF decline rate was calculated by dividing RRF difference between baseline to 12 month by period.RESULTS:
Mean RRF decline rate (mL/min/1.73m2/month) was negatively correlated with left ventricular posterior wall thickness (LVPWT) (R2=0.097, p=0.023) and proteinuria (R2=0.126, p=0.003), whereas positively correlated with hematocrit (R2=0.076, p=0.013) at baseline.CONCLUSION:
Decline of RRF during a year after commencement of PD was associated with baseline proteinuria and LVPWT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Urea
/
Body Surface Area
/
Retrospective Studies
/
Risk Factors
/
Peritoneal Dialysis
/
Peritoneal Dialysis, Continuous Ambulatory
/
Hypertrophy, Left Ventricular
/
Creatinine
/
Renal Insufficiency, Chronic
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2010
Type:
Article
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