Establishment and characterization of a targeting tumor vesseles system for inducing thrombosis / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 1508-1512, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-859980
ABSTRACT
METHODS:
Chemical cross-linking technique was used to prepare a cross-linking agent of the A6-Streptavidin (A6-SA), MF-A6-SA and Biotein-tTF (B-tTF). FX coagulation assay was used to test MF-A6-SAB-tTF system's FX activity. Fluorescence microscopy and prussian blue staining were used to simultaneously observe the targeting activity of MF-A6-SAB-tTF with an external magnetic field. Hemagglutination was directly used to study the system's biological amplification by SA/B. Biodistribution experiment was used to observe the toxicity of MF-A6-SAB-tTF.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2014
Type:
Article
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